PRF vs. PRP: Which Regenerative Treatment Is Right for You?
Quick answer: both use your own blood to rejuvenate skin, but PRF (platelet-rich fibrin) is the newer generation. It's spun gently with no additives, so it forms a natural fibrin scaffold that releases your growth factors slowly over one to two weeks — versus PRP, which stays liquid and releases them in a fast burst. That slow, steady release is why we build our regenerative treatments around PRF.
| PRF (Platelet-Rich Fibrin) | PRP (Platelet-Rich Plasma) | |
|---|---|---|
| Generation | Second-generation | First-generation |
| Additives | None (natural fibrin forms) | Anticoagulant added |
| Growth-factor release | Slow, steady over 1–2 weeks | Fast burst, early |
| Fibrin scaffold | Yes — holds cells in place | No — stays liquid |
| Best for skin | Gradual, natural rejuvenation | Shorter active window |
PRF's slow-release fibrin scaffold is why it's become the go-to for facial and under-eye rejuvenation — your own growth factors keep working for one to two weeks instead of a single burst. That's why our regenerative treatments are built on PRF. A consultation confirms the right plan for your goals.
What's the main difference between PRF and PRP?
PRF is spun gently with no anticoagulant, so it forms a natural fibrin scaffold that releases your growth factors slowly over one to two weeks. PRP uses an anticoagulant, stays liquid, and releases them in a fast early burst. PRF's gradual release is generally preferred for skin.
Is PRF better than PRP?
For skin rejuvenation, PRF's sustained growth-factor release is why it's largely replaced PRP in modern aesthetics. Both come from your own blood; PRF simply keeps working longer.
Does House of Rose use PRF or PRP?
We build our regenerative treatments around PRF (platelet-rich fibrin) — both topical PRF layered into needling and RN-performed PRF injections for the under-eyes.